Published on November 2021 | Bioactive Compounds

In-Silico ADMET Informatics of Geranyl Butyrate in Cymbopogon martinii Essential Oil

Worldwide interest in use of plants based natural products (PBNPs) has been growing, and its beneficial effects being rediscovered for the development of novel drugs. Literature survey on indigenous traditional knowledge bestows ethnopharmacological potentials of PBNPs that has inspired current research in drug design and discovery; PBNPs provide baseline for the development of novel drug leads against various pharmacological targets. Studies indicate that Cymbopogon martini Essential Oil (CMEO) exhibit wide range of biological activities such as hepatoprotective, antifungal, insecticide, antioxidant and antibacterial. Pharmacological properties of CMEO may be attributed to the presence of Geranyl butyrate. Therefore, physiochemical, drugable and ADMET properties have been envisaged in the present study.