Published on December 2020 | Bioactive Compounds, Pharmacoinformatics, Plant Based Natural Products

Profile of Pharmacologically Active Phyto-Compounds in Rosmarinus officinalis L. (Rosemary) Essential Oil

Plant Based Natural Products (PBNPs) have contributed to the development of many drugs for diverse indications. Worldwide interest in use of plants based natural products (PBNPs) has been growing, and its beneficial effects being rediscovered for the development of new drugs. Literature survey on indigenous traditional knowledge bestows ethnopharmacological potentials of PBNPs, which has inspired current research in drug discovery; PBNPs provide baseline for the development of novel drug leads against various pharmacological targets. Studies report that rosemary essential oil (REO) extracts in particular show biological bioactivities such as hepatoprotective, antifungal, insecticide, antioxidant and antibacterial. It is well known that the biological properties in rosemary are mainly due to phenolic compounds. However, their application is limited because of their odor, color and taste. Owing to the widespread applications of phytocompounds in REO - GCMS was performed. GCMS analysis detected 22 compounds of which 6 compounds were in abundant. Their ADMET properties were evaluated to ponder its application.